Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801568 | 0.78 | RAB9A (0.53) | MAPTTP53KMT2ANPC1 | |
| SCHEMBL10647488 | 0.77 | CYP1A2 (0.64) | CYP1A2CYP19A1CYP2C9CYP2C19MAPT | |
| SCHEMBL28746964 | 0.73 | CYP1A2 (0.54) | CYP1A2CYP19A1CYP2C9CYP2C19MAPT | |
| SCHEMBL2270503 | 0.73 | NPC1 (0.59) | CYP1A2CYP19A1CYP2C9CYP2C19MAPT | |
| SCHEMBL24307626 | 0.71 | NPC1 (0.58) | CYP1A2CYP19A1CYP2C9CYP2C19MAPT | |
| Ammonia Solution, Strong SCHEMBL28862474 | 0.71 | NPC1 (0.58) | CYP1A2CYP19A1CYP2C9CYP2C19MAPT | |
| SCHEMBL4665396 | 0.71 | CA2 (0.88) | CA2CA9CA1CA12 | |
| SCHEMBL18256160 | 0.71 | MAPT (0.52) | CYP1A2CYP19A1CYP2C9CYP2C19MAPT | |
| SCHEMBL2272084 | 0.70 | CYP1A2 (0.54) | CYP1A2CYP19A1CYP2C9CYP2C19MAPT | |
| SCHEMBL13514282 | 0.70 | CYP1A2 (0.54) | CYP1A2CYP19A1CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |