Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.53 |
| ▸ | NPC1 | O15118 | 9/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805906 | 0.78 | CYP1A2 (0.55) | NPC1TP53MAPTKMT2A | |
| SCHEMBL6802996 | 0.78 | TP53 (0.68) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL3219488 | 0.76 | RAB9A (0.72) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL10153708 | 0.76 | ALDH1A1 (0.67) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL21446983 | 0.75 | ROCK2 (0.59) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL22322454 | 0.75 | HPGD (0.55) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL19245571 | 0.71 | ROCK2 (0.57) | RAB9ANPC1SMN1; SMN2TP53MAPT | |
| SCHEMBL21536740 | 0.70 | ALDH1A1 (0.62) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL3236082 | 0.69 | ROCK2 (0.49) | RAB9ANPC1SMN1; SMN2HPGDTP53 | |
| SCHEMBL24376430 | 0.68 | MLLT1 (0.71) | RAB9ANPC1SMN1; SMN2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |