Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 6/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031006 | 0.83 | MAPT (0.48) | ADRB1MAPTALDH1A1HTR1ASMN1; SMN2 | |
| SCHEMBL6031040 | 0.82 | MAPT (0.52) | ADRB1MAPTALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL6032145 | 0.81 | MAPT (0.51) | ADRB1MAPTALDH1A1DRD4HTR1A | |
| SCHEMBL6030940 | 0.77 | ADRB1 (0.49) | ADRB1ALDH1A1CYP2D6HTTSMN1; SMN2 | |
| Bromide SCHEMBL6030911 | 0.77 | MEN1 (0.55) | ADRB1MAPTALDH1A1TSHRHTR1A | |
| SCHEMBL18387991 | 0.76 | MAPT (0.58) | ADRB1MAPTALDH1A1GAADRD4 | |
| SCHEMBL13085315 | 0.75 | NPY2R (0.60) | MAPTALDH1A1TSHRGAA | |
| SCHEMBL5023627 | 0.71 | CACNA2D1 (0.56) | MAPTALDH1A1TSHRGAAHTT | |
| SCHEMBL14038303 | 0.71 | HTR1A (0.67) | DRD4HTR1A | |
| SCHEMBL6411602 | 0.70 | HTR1A (0.52) | ADRB1ALDH1A1DRD4HTR1AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040083447-A1 | 1-Phenyl-4-benzylpiperazines dopamine receptor subtype specific ligands | NEUROGEN CORPORATION, A CORPORATION OF THE STATE OF DELAWARE | 2004-04-29 | — | — | US | claimed |