Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 9/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ATP4A | P20648 | 3/20 | 0.41 |
| ▸ | ATP4B | P51164 | 3/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806325 | 0.83 | PARP1 (0.62) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL6805633 | 0.82 | PARP1 (0.44) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL6805412 | 0.81 | MAPK14 (0.46) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL17048129 | 0.79 | KDM4E (0.56) | KMT2AKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL6802033 | 0.77 | FGFR1 (0.51) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL3579908 | 0.75 | PARP1 (0.61) | KDM4EALDH1A1HPGDPARP1 | |
| SCHEMBL6805769 | 0.74 | KDM4E (0.37) | KDM4EALDH1A1MAPTNPSR1PARP1 | |
| SCHEMBL6805352 | 0.74 | PARP1 (0.44) | PARP1CHEK1FGFR1KDRBTK | |
| SCHEMBL6806909 | 0.73 | KDM4E (0.38) | KDM4EALDH1A1LMNAHSD17B10PARP1 | |
| SCHEMBL871830 | 0.73 | PARP1 (0.58) | HSD17B10PARP1CHEK1FGFR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696437-B1 | Heterocyclically substituted benzimidazoles, the production and application thereof | ABBOTT GMBH & CO. KG (DE) | 2004-02-24 | — | — | US | disclosed |