Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812308 | 0.81 | ALDH1A1 (0.48) | ADRA2AADRA2BADRA2CADRA1AADRB3 | |
| SCHEMBL8186657 | 0.80 | PIK3CD (0.45) | ADRB3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2306775 | 0.77 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL6806493 | 0.77 | PKM (0.47) | ADRA2AADRA2BADRA2CADRA1AADRB3 | |
| SCHEMBL1913762 | 0.76 | ERBB2 (0.62) | EP300ALDH1A1GAAHTTLMNA | |
| SCHEMBL6802301 | 0.76 | CA1 (0.50) | ADRA2AADRA2BADRA2CADRA1AADRB3 | |
| SCHEMBL6806504 | 0.75 | PIK3CD (0.41) | ADRA2AADRA2BADRA2CADRA1AADRB3 | |
| SCHEMBL16200088 | 0.74 | ALDH1A1 (0.63) | ADRA2AADRA2BADRA2CADRA1AADRB3 | |
| SCHEMBL6811137 | 0.74 | POLB (0.49) | ALDH1A1GAALMNAHSD17B10CA1 | |
| SCHEMBL6802561 | 0.73 | SMN1; SMN2 (0.38) | ADRA2AADRA2BADRA2CADRA1AADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | claimed |
| US-20020100125-A1 | Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring | L'OREAL (FR) | 2002-08-01 | — | — | US | claimed |
| EP-1205176-A1 | Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing | L'OREAL (FR) | 2002-05-15 | — | — | EP | claimed |
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | disclosed |
| US-20020100125-A1 | Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring | L'OREAL (FR) | 2002-08-01 | — | — | US | disclosed |
| EP-1205176-A1 | Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing | L'OREAL (FR) | 2002-05-15 | — | — | EP | disclosed |