Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806745 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2ADRB3 | |
| SCHEMBL27559811 | 0.82 | PKM (0.45) | PKMALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2445950 | 0.81 | ALDH1A1 (0.46) | PKMALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6806791 | 0.80 | MEN1 (0.54) | ALDH1A1MEN1KMT2ABRD4KDM4E | |
| SCHEMBL6807571 | 0.77 | ALDH1A1 (0.56) | PKMALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6806453 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6806487 | 0.77 | ADRA2A (0.45) | ALDH1A1MEN1KMT2ASMN1; SMN2CA1 | |
| SCHEMBL11130061 | 0.76 | RECQL (0.41) | MEN1KMT2AADRB3ADRA2AADRA2B | |
| SCHEMBL4667299 | 0.75 | KDM4E (0.45) | PKMALDH1A1MEN1KMT2ACA1 | |
| SCHEMBL7251847 | 0.75 | KDM4E (0.45) | PKMALDH1A1CA1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | claimed |
| US-20020100125-A1 | Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring | L'OREAL (FR) | 2002-08-01 | — | — | US | claimed |
| EP-1205176-A1 | Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing | L'OREAL (FR) | 2002-05-15 | — | — | EP | claimed |
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | disclosed |
| US-20020100125-A1 | Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring | L'OREAL (FR) | 2002-08-01 | — | — | US | disclosed |
| EP-1205176-A1 | Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing | L'OREAL (FR) | 2002-05-15 | — | — | EP | disclosed |