SCHEMBL6806548

SCHEMBL6806548

CC(=O)Nc1cccc(O)c1NS(C)(=O)=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 2/20 0.43
TSHR P16473 2/20 0.43
HPGD P15428 1/20 0.43
MAOA P21397 1/20 0.43
EP300 Q09472 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT8 Q9H7Z6 1/20 0.41
CASP6 P55212 1/20 0.41
PIP4K2A P48426 1/20 0.41
PIP4K2B P78356 1/20 0.41
KEAP1 Q14145 2/20 0.41
NPC1 O15118 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
NFE2L2 Q16236 1/20 0.41
CYP1A2 P05177 1/20 0.41
PLA2G7 Q13093 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6807397 0.83 KMT2A (0.61) ALDH1A1SMN1; SMN2LMNATSHRMAPT
SCHEMBL249105 0.83 ALDH1A1 (0.52) ALDH1A1TSHRHPGDMAOANPC1
SCHEMBL7669371 0.80 EP300 (0.48) ALDH1A1SMN1; SMN2EP300KAT2BKAT8
SCHEMBL7573299 0.80 KEAP1 (0.47) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL27272493 0.78 TSHR (0.61) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL28750618 0.77 KMT2A (0.60) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL4047702 0.74 ALDH1A1 (0.55) ALDH1A1TSHRHPGDMAOANPC1
Sulfuric Acid SCHEMBL9615897 0.74 GAA (0.56) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL19004112 0.73 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2TSHRHPGDMAOA
SCHEMBL9400517 0.73 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2LMNAHPGDMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed