Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6806702 | 0.87 | KEAP1 (0.59) | KEAP1NFE2L2HPGDTSHRKMT2A | |
| SCHEMBL4959475 | 0.85 | ALDH1A1 (0.59) | ALDH1A1HPGDTSHRSMN1; SMN2KMT2A | |
| SCHEMBL27272493 | 0.84 | TSHR (0.61) | KEAP1ALDH1A1HPGDTSHRSMN1; SMN2 | |
| SCHEMBL28750618 | 0.83 | KMT2A (0.60) | KEAP1NFE2L2ALDH1A1HPGDTSHR | |
| SCHEMBL6806548 | 0.80 | ALDH1A1 (0.43) | KEAP1NFE2L2ALDH1A1HPGDTSHR | |
| SCHEMBL7569074 | 0.77 | PSIP1 (0.51) | KEAP1NFE2L2KMT2AEP300KAT2B | |
| SCHEMBL19004112 | 0.76 | ALDH1A1 (0.53) | ALDH1A1HPGDTSHRSMN1; SMN2KMT2A | |
| SCHEMBL2642081 | 0.75 | KEAP1 (0.50) | KEAP1NFE2L2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL15649605 | 0.75 | KEAP1 (0.50) | KEAP1NFE2L2ALDH1A1HPGDTSHR | |
| SCHEMBL6697979 | 0.74 | ALDH1A1 (0.68) | ALDH1A1HPGDSMN1; SMN2KMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020100125-A1 | Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring | L'OREAL (FR) | 2002-08-01 | — | — | US | claimed |