SCHEMBL5582630

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9705548	0.89	NR1H4 (0.56)	MCHR1KMT2AALDH1A1MEN1HTT
	SCHEMBL6806574	0.89	HSD17B1 (0.65)	MCHR1HSD17B1HSD17B2KMT2AALDH1A1
	SCHEMBL12595515	0.86	ESR1 (0.50)	KMT2AMEN1KDM4EHPGDACHE
	SCHEMBL12550510	0.86	HSP90AA1 (0.49)	KMT2AALDH1A1MEN1HTTHSP90AA1
	SCHEMBL11988235	0.86	MCHR1 (0.47)	MCHR1HSD17B1HSD17B2KMT2AALDH1A1
	SCHEMBL4090142	0.83	HSD17B1 (0.58)	MCHR1HSD17B1HSD17B2KMT2AALDH1A1
	SCHEMBL5582735	0.83	CA1 (0.67)	MCHR1HSD17B1HSD17B2KMT2AALDH1A1
	SCHEMBL12595526	0.82	MCHR1 (0.48)	MCHR1HSD17B2KMT2AMEN1KDM4E
	SCHEMBL7376311	0.81	HSD17B1 (0.57)	MCHR1HSD17B1HSD17B2KMT2AALDH1A1
	SCHEMBL17211642	0.81	ALDH1A1 (0.53)	KMT2AALDH1A1HTTPDK2PDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.