Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.41 |
| ▸ | ITGAV | P06756 | 3/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640112 | 0.85 | ITGB3 (0.51) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL6801814 | 0.85 | HTR2C (0.34) | HTR2CKMT2AMAPT | |
| SCHEMBL6805791 | 0.82 | ITGB3 (0.44) | ITGB3ITGAVITGA2BKMT2AMAPT | |
| SCHEMBL4640676 | 0.81 | KMT2A (0.36) | HTR2CKMT2AMEN1MAPT | |
| SCHEMBL6803682 | 0.81 | ITGB3 (0.45) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL6805793 | 0.79 | ITGB3 (0.41) | ITGB3ITGAVITGA2BKMT2AMAPT | |
| SCHEMBL4641339 | 0.75 | STAT3 (0.38) | ITGB3ITGAVHTR2CKMT2AMEN1 | |
| SCHEMBL4640102 | 0.75 | ITGB3 (0.34) | ITGB3ITGAVITGA2BHTR2CKMT2A | |
| SCHEMBL6876023 | 0.74 | SIRT2 (0.36) | HTR2CKMT2AMEN1MAPT | |
| SCHEMBL4640085 | 0.71 | ITGAV (0.38) | ITGB3ITGAVITGA2BMAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |