Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.51 |
| ▸ | ITGAV | P06756 | 15/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805791 | 0.92 | ITGB3 (0.44) | ITGB3ITGAVITGA2BKMT2AMAPT | |
| SCHEMBL4640085 | 0.86 | ITGAV (0.38) | ITGB3ITGAVITGA2BSTAT3MAPT | |
| SCHEMBL6803682 | 0.86 | ITGB3 (0.45) | ITGB3ITGAVITGA2BKMT2AMEN1 | |
| SCHEMBL4640251 | 0.86 | ITGB3 (0.49) | ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL6806684 | 0.85 | ITGB3 (0.41) | ITGB3ITGAVITGA2BSTAT3KMT2A | |
| SCHEMBL6805793 | 0.82 | ITGB3 (0.41) | ITGB3ITGAVITGA2BKMT2AMAPT | |
| SCHEMBL4640102 | 0.81 | ITGB3 (0.34) | ITGB3ITGAVITGA2BSTAT3KMT2A | |
| Benzene SCHEMBL6884463 | 0.81 | ITGB3 (0.40) | ITGB3ITGAVITGA2BSTAT3KMT2A | |
| SCHEMBL4641013 | 0.80 | ITGB3 (0.34) | ITGB3ITGAVITGA2BSTAT3KMT2A | |
| SCHEMBL4641339 | 0.80 | STAT3 (0.38) | ITGB3ITGAVSTAT3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853084-B1 | Substituted purine derivatives as vitronectin receptor antagonists | HOECHST AG (DE) | 2008-08-13 | — | — | EP | disclosed |
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |
| EP-0853084-A2 | Substituted purine derivatives as vitronectin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-15 | — | — | EP | disclosed |