Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.59 |
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.53 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569074 | 0.89 | PSIP1 (0.51) | KEAP1NFE2L2EP300KAT2BKAT8 | |
| SCHEMBL7573299 | 0.87 | KEAP1 (0.47) | KEAP1NFE2L2EP300KAT2BKAT8 | |
| SCHEMBL2642081 | 0.86 | KEAP1 (0.50) | KEAP1NFE2L2EP300KAT2BKAT8 | |
| SCHEMBL15649605 | 0.86 | KEAP1 (0.50) | KEAP1NFE2L2EP300KAT2BKAT8 | |
| SCHEMBL8607408 | 0.85 | GABRA1 (0.55) | KEAP1NFE2L2EP300KAT2BKAT8 | |
| SCHEMBL2068498 | 0.80 | KEAP1 (0.65) | KEAP1NFE2L2EP300KAT2BKAT8 | |
| SCHEMBL29904739 | 0.80 | KEAP1 (0.65) | KEAP1NFE2L2EP300KAT2BKAT8 | |
| SCHEMBL6111717 | 0.80 | EP300 (0.61) | KEAP1NFE2L2EP300KAT2BKAT8 | |
| SCHEMBL5965425 | 0.79 | KEAP1 (0.67) | KEAP1NFE2L2EP300KAT2BKAT8 | |
| SCHEMBL11509065 | 0.79 | KEAP1 (0.77) | KEAP1NFE2L2EP300KAT2BKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | claimed |
| US-20020100125-A1 | Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring | L'OREAL (FR) | 2002-08-01 | — | — | US | claimed |
| EP-1205176-A1 | Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing | L'OREAL (FR) | 2002-05-15 | — | — | EP | claimed |
| US-6733540-B2 | FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES | L'OREAL (FR) | 2004-05-11 | — | — | US | disclosed |
| EP-1205176-A1 | Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing | L'OREAL (FR) | 2002-05-15 | — | — | EP | disclosed |