SCHEMBL9703261

SCHEMBL9703261

CS(=O)(=O)c1ccc(NN)c(Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.71
CA1 P00915 6/20 0.71
CA9 Q16790 3/20 0.71
PDK1 Q15118 1/20 0.51
PDK2 Q15119 1/20 0.51
PDK3 Q15120 1/20 0.51
PDK4 Q16654 1/20 0.51
LRRK2 Q5S007 3/20 0.49
ALDH1A1 P00352 2/20 0.46
MAPT P10636 1/20 0.46
LMNA P02545 1/20 0.46
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
USP28 Q96RU2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3952309 0.83 CA2 (1.00) CA2CA1CA9
SCHEMBL11721290 0.81 CA2 (0.71) CA2CA1CA9ALDH1A1
Hydrochloric Acid SCHEMBL3956184 0.81 CA2 (0.96) CA2CA1CA9
SCHEMBL6807006 0.79 CA1 (0.44) CA2CA1CA9ALDH1A1MAPT
SCHEMBL9135441 0.79 SMN1; SMN2 (0.50) CA2CA1CA9PDK1PDK2
SCHEMBL10834108 0.79 PDK1 (0.49) CA2CA1CA9PDK1PDK2
SCHEMBL10834105 0.79 PDK1 (0.49) CA2CA1CA9PDK1PDK2
Hydrochloric Acid SCHEMBL6511653 0.78 CA1 (0.43) CA2CA1CA9ALDH1A1MAPT
SCHEMBL1243294 0.78 CA1 (0.71) CA2CA1CA9
SCHEMBL23144587 0.77 PDK1 (0.62) CA2CA1CA9PDK1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014126580-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2014-08-21 WO disclosed
WO-2013106254-A1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2013-07-18 WO disclosed
US-5109036-A With alkysulfonylphenylhydrazine accelerator; storage stability CECA, S.A. (FR) 1992-04-28 US disclosed
EP-0443916-A1 Anaerobically curing adhesive compositions CECA S.A. (FR) 1991-08-28 EP disclosed