SCHEMBL6807072

SCHEMBL6807072

CC(=O)Nc1ccc(NS(C)(=O)=O)c(O)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.51
ADRB3 P13945 1/20 0.51
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
POLB P06746 2/20 0.49
EP300 Q09472 1/20 0.49
KAT2B Q92831 1/20 0.49
KAT8 Q9H7Z6 1/20 0.49
MAPT P10636 3/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
CA12 O43570 3/20 0.47
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA9 Q16790 3/20 0.47
PIP4K2A P48426 2/20 0.47
PIP4K2B P78356 2/20 0.47
HPGD P15428 1/20 0.46
MEN1 O00255 1/20 0.46
BRD4 O60885 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15894591 0.87 ADRB3 (0.60) PKMADRB3ALDH1A1SMN1; SMN2EP300
SCHEMBL9095123 0.85 TDP1 (0.47) PKMADRB3ALDH1A1SMN1; SMN2POLB
SCHEMBL6806587 0.84 SMN1; SMN2 (0.48) ALDH1A1SMN1; SMN2POLBEP300KAT2B
SCHEMBL6571944 0.83 GSTO1 (0.50) ALDH1A1SMN1; SMN2EP300KAT2BKAT8
SCHEMBL3238696 0.83 NPC1 (0.54) ALDH1A1SMN1; SMN2EP300KAT2BKAT8
SCHEMBL4958020 0.83 MAPT (0.69) PKMALDH1A1SMN1; SMN2POLBMAPT
SCHEMBL6805921 0.81 KMT2A (0.62) PKMALDH1A1SMN1; SMN2POLBMAPT
SCHEMBL3247691 0.80 TOP1 (0.60) SMN1; SMN2EP300KAT2BKAT8MAPT
SCHEMBL3236934 0.80 NPC1 (0.51) ADRB3ALDH1A1SMN1; SMN2EP300KAT2B
SCHEMBL3237191 0.80 TOP1 (0.60) SMN1; SMN2EP300KAT2BKAT8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US claimed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US claimed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP claimed
US-6733540-B2 FOR USE IN OXIDATION DYEING OF KERATINOUS FIBRES L'OREAL (FR) 2004-05-11 US disclosed
US-20020100125-A1 Use of 2-(sulphonylamino) phenols as couplers in oxidation colouring L'OREAL (FR) 2002-08-01 US disclosed
EP-1205176-A1 Use of 2-sulphonylaminophenols as coupling agents in oxidation dyeing L'OREAL (FR) 2002-05-15 EP disclosed