Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.56 |
| ▸ | PANK3 | Q9H999 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | SMO | Q99835 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941941 | 0.94 | GPR119 (0.61) | GPR119PANK3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL231983 | 0.85 | KDM4E (0.51) | GPR119PANK3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30390836 | 0.85 | KDM4E (0.51) | GPR119PANK3KDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL23302464 | 0.84 | KDM4E (0.50) | GPR119PANK3KDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL21521443 | 0.84 | KDM4E (0.50) | GPR119PANK3KDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30731344 | 0.84 | KDM4E (0.50) | GPR119PANK3KDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL17455098 | 0.84 | KDM4E (0.50) | GPR119PANK3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2003952 | 0.80 | KDR (0.50) | GPR119PANK3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6809004 | 0.79 | GAA (0.60) | GPR119KDM4EALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL31465050 | 0.79 | KDR (0.49) | GPR119PANK3KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | MMP9, MMP10, MMP3 | GPR119 4215/4885PANK3 3981/4885KDM4E 1770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.