Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 5/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | USP21 | Q9UK80 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | FCER2 | P06734 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CENPE | Q02224 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807421 | 1.00 | NPC1 (0.62) | NPC1RAB9ATP53SMN1; SMN2CA2 | |
| SCHEMBL27659000 | 0.87 | CA2 (0.67) | NPC1RAB9ATP53SMN1; SMN2CA2 | |
| SCHEMBL4366751 | 0.87 | CA2 (0.67) | NPC1RAB9ATP53SMN1; SMN2CA2 | |
| SCHEMBL6802085 | 0.87 | ALDH1A1 (0.53) | CA2MMP1MMP3MEN1KMT2A | |
| SCHEMBL6802093 | 0.87 | ALDH1A1 (0.53) | CA2MMP1MMP3MEN1KMT2A | |
| SCHEMBL4362723 | 0.86 | ALDH1A1 (0.59) | NPC1RAB9ATP53SMN1; SMN2CA2 | |
| SCHEMBL13956888 | 0.86 | CTSL (0.70) | CTSLCTSSCTSKMMP1FCER2 | |
| SCHEMBL1351202 | 0.85 | CTSL (0.56) | NPC1RAB9ATP53SMN1; SMN2CA2 | |
| SCHEMBL4368609 | 0.85 | RAB9A (0.60) | NPC1RAB9ATP53SMN1; SMN2CA2 | |
| SCHEMBL6800540 | 0.85 | NPC1 (0.59) | NPC1RAB9ATP53SMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074238-A1 | PHENETHYLAMINO SULFAMIC ACIDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-09-02 | — | — | WO | disclosed |
| US-20040167183-A1 | Phenethylamino sulfamic acids | THE PROCTER & GAMBLE COMPANY | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167183-A1 | Phenethylamino sulfamic acids | PTPRM, PTPRS, PTPRE | NPC1 4576/4885RAB9A 3191/4885TP53 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.