Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Methoxymethane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8447847 | 0.92 | CA1 (0.35) | CA1CA2 | |
| SCHEMBL10284634 | 0.89 | CA1 (0.36) | CA1CA2CA9 | |
| SCHEMBL4754119 | 0.81 | CA1 (0.32) | CA1CA2CA9 | |
| SCHEMBL4754123 | 0.80 | CA1 (0.33) | CA1CA2CA9 | |
| SCHEMBL3325276 | 0.71 | TSHR (0.43) | CA1CA2CA9 | |
| Water SCHEMBL28967704 | 0.64 | HPGD (0.32) | — | |
| SCHEMBL31391948 | 0.61 | — | — | |
| Methoxymethane SCHEMBL28069910 | 0.60 | USP2 (0.38) | CA1CA2 | |
| SCHEMBL30557104 | 0.59 | — | — | |
| SCHEMBL339794 | 0.59 | HSD17B10 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058857-A1 | Method of treating cancer | YAO SIU-LONG (US) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058857-A1 | Method of treating cancer | KLK3, SHBG, ACP3 | CA1 78/4885CA2 572/4885CA9 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.