Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732202 | 0.92 | PDE4B (0.57) | AOC3PDE4BGAAHTTNPSR1 | |
| SCHEMBL9732195 | 0.92 | PDE4B (0.57) | AOC3PDE4BGAAHTTNPSR1 | |
| SCHEMBL7832869 | 0.90 | PDE4B (0.55) | AOC3PDE4BGAAHTTNPSR1 | |
| SCHEMBL8015785 | 0.89 | PDE4B (0.54) | AOC3PDE4BGAAHTTNPSR1 | |
| SCHEMBL5490631 | 0.87 | PDE4B (0.53) | AOC3PDE4BGAAFFAR1ALDH1A1 | |
| SCHEMBL2512731 | 0.85 | AOC3 (0.54) | AOC3GAAHTTNPSR1RAB9A | |
| SCHEMBL6831514 | 0.84 | AOC3 (0.49) | AOC3PDE4BGAAALDH1A1MAPT | |
| SCHEMBL27590253 | 0.83 | PDE4B (0.50) | PDE4BGAAHTTNPSR1FFAR1 | |
| SCHEMBL4478662 | 0.82 | FFAR1 (0.56) | AOC3FFAR1L3MBTL1LDHAKMT2A | |
| SCHEMBL4478666 | 0.82 | FFAR1 (0.56) | AOC3FFAR1L3MBTL1LDHAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| US-20040014993-A1 | Novel chemo-enzymatic process for the preparation of opticaly enriched beta-benzyl-gamma-butyrolactones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2004-01-22 | — | — | US | disclosed |
| US-6646106-B1 | Polymerizing chiral diphosphine having a C2 axis of symmetry, with one or several polymerizable monomers, said chiral diphosphine consisting of a chiral body bearing two identical functional groups | RHODIA CHIMIE (FR) | 2003-11-11 | — | — | US | disclosed |
| US-6166257-A | METAL COMPLEX OF AN OPTICALLY ACTIVE BIS(1-PHOSPHA-2,3-DIPHENYL-4,5-DIMETHYLNORBORNADIENE) | RHODIA CHIMIE (FR) | 2000-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014993-A1 | Novel chemo-enzymatic process for the preparation of opticaly enriched beta-benzyl-gamma-butyrolactones | BBOX1, BCHE, AOX1 | AOC3 16/4885PDE4B 1621/4885GAA 660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.