Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.57 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | PTGFR | P43088 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732195 | 1.00 | PDE4B (0.57) | PDE4BAOC3GAAHTTNPSR1 | |
| SCHEMBL5490631 | 0.95 | PDE4B (0.53) | PDE4BAOC3GAAFFAR1ALDH1A1 | |
| SCHEMBL7832869 | 0.95 | PDE4B (0.55) | PDE4BAOC3GAAHTTNPSR1 | |
| SCHEMBL8015785 | 0.94 | PDE4B (0.54) | PDE4BAOC3GAAHTTNPSR1 | |
| SCHEMBL6807907 | 0.92 | AOC3 (0.51) | PDE4BAOC3GAAHTTNPSR1 | |
| SCHEMBL9391332 | 0.83 | PDE4B (0.57) | PDE4BHTTNPSR1FFAR1NPC1 | |
| SCHEMBL6831514 | 0.82 | AOC3 (0.49) | PDE4BAOC3GAAALDH1A1MAPT | |
| SCHEMBL2743314 | 0.81 | KMT2A (0.47) | FFAR1L3MBTL1PTGFRKMT2A | |
| SCHEMBL4478662 | 0.81 | FFAR1 (0.56) | AOC3FFAR1L3MBTL1LDHAKMT2A | |
| SCHEMBL4478666 | 0.81 | FFAR1 (0.56) | AOC3FFAR1L3MBTL1LDHAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220442-A1 | PEGylated Recombinant Human Growth Hormone Compounds | ASCENDIS PHARMA ENDOCRINOLOGY DIVISION A/S (DK) | 2021-07-22 | — | — | US | disclosed |
| CN-107827952-A | One plan peptides with the protease inhibiting activities of HIV 1 newly and its production and use | 中国医学科学院医药生物技术研究所 | 2018-03-23 | — | — | CN | disclosed |
| US-5149462-A | Used as ferroelectric liquid crystal | MITSUBISHI RAYON COMPANY LTD. (JP) | 1992-09-22 | — | — | US | disclosed |
| EP-0409066-A2 | Optically active compound for liquid crystal and its use | MITSUBISHI RAYON COMPANY, LTD. (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4839360-A | ANTIDEPRESSANTS; NERVOUS AND PSYCHOLOGICAL DISORDERS; COGNITION ACTIVATORS | TANABE SEIYAKU CO., LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| EP-0270093-A2 | Lactam derivatives, processes for the preparation thereof, pharmaceutical compositions comprising the same, and the use of such derivatives for the manufacture of a medicament having valuable therapeutic properties | TANABE SEIYAKU CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220442-A1 | PEGylated Recombinant Human Growth Hormone Compounds | GHRHR, GHITM, GHSR | PDE4B 4386/4885AOC3 4003/4885GAA 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.