Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | FGB | P02675 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8265768 | 0.89 | ADORA2A (0.41) | EGFRMAPTPABPC1MAPK1RAB9A | |
| SCHEMBL8204670 | 0.89 | MAPT (0.57) | EGFRMAPTPABPC1MAPK1RAB9A | |
| SCHEMBL3087928 | 0.83 | MAPK1 (0.67) | EGFRMAPTPABPC1MAPK1RAB9A | |
| SCHEMBL125609 | 0.82 | NSD2 (0.55) | MAPTMAPK1SMN1; SMN2TDP1ADORA2A | |
| SCHEMBL5573806 | 0.82 | EGFR (0.71) | EGFRMAPTPABPC1MAPK1RAB9A | |
| SCHEMBL4123519 | 0.79 | MAPT (0.56) | EGFRMAPTPABPC1MAPK1RAB9A | |
| SCHEMBL7193552 | 0.77 | MAOA (0.74) | SMN1; SMN2MAOACASP3TERT | |
| SCHEMBL9846483 | 0.77 | MAOA (0.74) | SMN1; SMN2MAOACASP3TERT | |
| Anthraquinone SCHEMBL5172785 | 0.77 | ADORA2A (0.57) | EGFRMAPTPABPC1MAPK1RAB9A | |
| SCHEMBL1476410 | 0.77 | ADORA2A (0.57) | MAPTMAPK1SMN1; SMN2TDP1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824998-B2 | FOR DETERMINATION IN MAMMALS VIA 1-ANTHRAQUINONYLHYDRAZIDE WITH P-ANIALDEHYDE; DRUG SCREENING; PACKAGING; KITS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2004-11-30 | — | — | US | disclosed |
| US-20040185520-A1 | Compounds and methods for detecting tripeptidyl protease I | AKRION, INC. | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040185520-A1 | Compounds and methods for detecting tripeptidyl protease I | TPP1, DNPEP, TPP2 | EGFR 4376/4885MAPT 4541/4885PABPC1 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.