SCHEMBL4123519

SCHEMBL4123519

NNc1cccc2c1C(=O)c1ccccc1-2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
MAPK1 P28482 3/20 0.56
RAB9A P51151 2/20 0.56
EGFR P00533 1/20 0.56
PABPC1 P11940 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MAOA P21397 4/20 0.50
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
LMNA P02545 4/20 0.49
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 2/20 0.49
HTT P42858 2/20 0.48
CYP1A2 P05177 2/20 0.47
ADORA2A P29274 2/20 0.47
FGR P09769 1/20 0.47
PIM1 P11309 1/20 0.47
CSNK1A1 P48729 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3087928 0.92 MAPK1 (0.67) MAPTSMN1; SMN2MAPK1RAB9AEGFR
SCHEMBL8204670 0.90 MAPT (0.57) MAPTSMN1; SMN2MAPK1RAB9AEGFR
SCHEMBL7568552 0.83 ALDH1A1 (0.43) MAPTSMN1; SMN2MAPK1RAB9AEGFR
SCHEMBL11570298 0.80 MAPT (0.56) MAPTSMN1; SMN2MAPK1RAB9AEGFR
SCHEMBL6807955 0.79 EGFR (0.47) MAPTSMN1; SMN2MAPK1RAB9AEGFR
SCHEMBL8267276 0.79 L3MBTL1 (0.51) MAPTSMN1; SMN2MAPK1RAB9AEGFR
SCHEMBL5563589 0.77 MAOA (0.55) MAPTSMN1; SMN2MAPK1RAB9AEGFR
SCHEMBL24645618 0.76 MAPT (0.71) MAPTSMN1; SMN2MAPK1RAB9AEGFR
SCHEMBL42481 0.75 MAPT (0.71) MAPTSMN1; SMN2MAPK1RAB9AEGFR
SCHEMBL11167085 0.75 MAPT (0.71) MAPTSMN1; SMN2MAPK1RAB9AEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7479357-B2 Substituted 9H-fluorenone hydrazones SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-01-20 US disclosed
EP-1293837-B1 Electrophotographic organophotoreceptors SAMSUNG ELECTRONICS CO LTD (KR) 2008-10-08 EP disclosed
CN-1297855-C Organic photoreceptor of electronic photograph SAMSUNG ELECTRONICS CO LTD (KR) 2007-01-31 CN disclosed
EP-1718705-A1 CATIONIC HETEROARYL AZINE DYES, AND DYEING AGENTS CONTAINING SAID COMPOUNDS Wella Aktiengesellschaft (DE) 2006-11-08 EP disclosed
WO-2005083009-A1 CATIONIC HETEROARYL AZINE DYES, AND DYEING AGENTS CONTAINING SAID COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 2005-09-09 WO disclosed
US-20050084784-A1 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO., LTD. 2005-04-21 US disclosed
EP-1293837-A3 Electrophotographic organophotoreceptors Samsung Electronics Co., Ltd. (KR) 2004-03-03 EP disclosed
US-20030104294-A1 Electrophotographic organophotoreceptors with novel charge transport materials SAMSUNG ELECTRONICS CO. LTD. 2003-06-05 US disclosed
CN-1416021-A Organic photoreceptor of electronic photograph SAMSUNG ELECTRONICS CO LTD (KR) 2003-05-07 CN disclosed
EP-1293837-A2 Electrophotographic organophotoreceptors Samsung Electronics Co., Ltd. (KR) 2003-03-19 EP disclosed
EP-1293837-A2 Electrophotographic organophotoreceptors Samsung Electronics Co., Ltd. (KR) 2003-03-19 EP disclosed
EP-0339444-A1 Elaiophylin derivatives, process for their preparation and use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1989-11-02 EP disclosed