Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808487 | 0.90 | ACHE (0.38) | ACHEBCHECHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8181319 | 0.85 | ADRB2 (0.36) | ACHEBCHECHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL2102802 | 0.85 | HPGD (0.54) | SMN1; SMN2ALDH1A1NAMPTHDAC3HDAC4 | |
| SCHEMBL5409417 | 0.83 | PSMB8 (0.41) | ALDH1A1 | |
| SCHEMBL17168743 | 0.82 | SMN1; SMN2 (0.50) | ACHEBCHECHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL26382038 | 0.82 | SMN1; SMN2 (0.50) | ACHEBCHECHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL17767809 | 0.82 | SMN1; SMN2 (0.50) | ACHEBCHECHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL17767812 | 0.82 | SMN1; SMN2 (0.50) | ACHEBCHECHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL20999873 | 0.82 | SMN1; SMN2 (0.50) | ACHEBCHECHRM2SMN1; SMN2ALDH1A1 | |
| SCHEMBL21117960 | 0.81 | SMN1; SMN2 (0.49) | ACHEBCHECHRM2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067229-A1 | Azobenzene derivatives as labeling agents and intermediates thereof | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2004-04-08 | — | — | US | disclosed |
| US-6602987-B1 | 4'-hydroxyazobenzene-2-carboxylic acid (HABA) compounds; useful as reagents for labeling, isolation and detection of biological molecules | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2003-08-05 | — | — | US | disclosed |
| WO-2000027813-A1 | AZOBENZENE DERIVATIVES AS LABELING AGENTS AND INTERMEDIATES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2000-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067229-A1 | Azobenzene derivatives as labeling agents and intermediates thereof | CBR1, CBR3, HBB | ACHE 2105/4885BCHE 124/4885CHRM2 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.