Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | APOB | P04114 | 7/20 | 0.45 |
| ▸ | MTTP | P55157 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805006 | 0.88 | MTTP (0.53) | TRPV1NPC1RAB9AAPOBMTTP | |
| SCHEMBL6796691 | 0.84 | KIF11 (0.50) | TRPV1NPC1RAB9AAPOBMTTP | |
| SCHEMBL6803896 | 0.84 | APOB (0.51) | APOBMTTPKDM4E | |
| Hydrochloric Acid SCHEMBL6804654 | 0.83 | APOB (0.51) | APOBMTTPKDM4E | |
| SCHEMBL13996052 | 0.82 | TRPV1 (0.56) | TRPV1NPC1RAB9AMAPTLMNA | |
| SCHEMBL13544352 | 0.77 | TRPV1 (0.61) | TRPV1NPC1RAB9AMAPTLMNA | |
| SCHEMBL6490383 | 0.76 | PTGS1 (0.58) | TRPV1NPC1RAB9AAPOBMTTP | |
| SCHEMBL6500905 | 0.75 | TRPV1 (0.50) | TRPV1NPC1RAB9AAPOBMTTP | |
| SCHEMBL13544376 | 0.75 | TRPV1 (0.61) | TRPV1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL3587856 | 0.74 | TRPV1 (0.52) | TRPV1NPC1RAB9AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | TRPV1 2399/4885NPC1 40/4885RAB9A 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.