Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.50 |
| ▸ | APOB | P04114 | 2/20 | 0.48 |
| ▸ | MTTP | P55157 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490621 | 0.89 | NPC1 (0.53) | NPC1RAB9ALMNATP53SMN1; SMN2 | |
| SCHEMBL6490383 | 0.87 | PTGS1 (0.58) | TRPV1APOBMTTPP2RX1TMPRSS4 | |
| SCHEMBL6687830 | 0.85 | P2RX1 (0.48) | TRPV1APOBMTTPP2RX1TMPRSS4 | |
| SCHEMBL6799567 | 0.84 | APOB (0.61) | TRPV1APOBMTTPRXFP1PTGS1 | |
| SCHEMBL6496388 | 0.83 | ABCG2 (0.56) | TRPV1APOBMTTPRXFP1P2RX1 | |
| SCHEMBL6489790 | 0.78 | TRPV1 (0.50) | TRPV1APOBMTTP | |
| SCHEMBL6501149 | 0.78 | TRPV1 (0.50) | TRPV1APOBMTTPNPC1RAB9A | |
| SCHEMBL6676886 | 0.78 | APOB (0.46) | TRPV1APOBMTTPRXFP1P2RX1 | |
| SCHEMBL7087379 | 0.78 | RXFP1 (0.57) | TRPV1APOBMTTPRXFP1P2RX1 | |
| SCHEMBL6488558 | 0.78 | LMNA (0.50) | TRPV1APOBMTTPP2RX1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | TRPV1 2245/4885APOB 1/4885MTTP 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.