Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941705 | 0.92 | CYP4F2 (0.51) | LMNACYP4F2CYP4A11MAPTALDH1A1 | |
| SCHEMBL6808548 | 0.91 | CYP4F2 (0.43) | LMNACYP4F2CYP4A11MAPTCYP1A2 | |
| SCHEMBL941980 | 0.82 | CYP4F2 (0.49) | LMNACYP4F2CYP4A11MAPTCYP1A2 | |
| SCHEMBL21293608 | 0.81 | CYP1A2 (0.47) | LMNACYP4F2CYP4A11MAPTALDH1A1 | |
| SCHEMBL1511082 | 0.76 | CYP4F2 (0.57) | LMNACYP4F2CYP4A11MAPTALDH1A1 | |
| SCHEMBL18989528 | 0.76 | MAPT (0.46) | LMNACYP4F2CYP4A11MAPTALDH1A1 | |
| SCHEMBL7890254 | 0.74 | CA12 (0.51) | LMNAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL16812136 | 0.74 | CYP4F2 (0.46) | LMNACYP4F2CYP4A11MAPTALDH1A1 | |
| SCHEMBL10729376 | 0.74 | MAPT (0.47) | LMNACYP4F2CYP4A11MAPTALDH1A1 | |
| SCHEMBL28419091 | 0.74 | CYP4F2 (0.59) | LMNACYP4F2CYP4A11MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | MMP9, MMP10, MMP3 | LMNA 1461/4885CYP4F2 709/4885CYP4A11 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.