Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 3/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.39 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941980 | 0.92 | CYP4F2 (0.49) | CYP4F2CYP4A11LMNACYP1A2CYP3A4 | |
| SCHEMBL6809067 | 0.91 | LMNA (0.46) | CYP4F2CYP4A11LMNACYP1A2CYP3A4 | |
| SCHEMBL941705 | 0.82 | CYP4F2 (0.51) | CYP4F2CYP4A11LMNASMN1; SMN2TOP2A | |
| SCHEMBL1859504 | 0.75 | CYP1A2 (0.57) | CYP4F2CYP4A11LMNACYP1A2CYP3A4 | |
| SCHEMBL31193477 | 0.73 | CYP1A2 (0.47) | CYP4F2CYP4A11LMNACYP1A2TOP2A | |
| SCHEMBL7890254 | 0.72 | CA12 (0.51) | LMNASMN1; SMN2MAPT | |
| SCHEMBL21293608 | 0.72 | CYP1A2 (0.47) | CYP4F2CYP4A11LMNACYP1A2CYP3A4 | |
| SCHEMBL20224965 | 0.72 | L3MBTL1 (0.51) | LMNAALOX5SMN1; SMN2 | |
| SCHEMBL20477208 | 0.71 | CYP4F2 (0.48) | CYP4F2CYP4A11LMNACYP1A2CYP3A4 | |
| SCHEMBL3937555 | 0.71 | SYK (0.50) | CYP4F2CYP4A11LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127528-A1 | Metalloproteinase inhibitors | MMP9, MMP10, MMP3 | CYP4F2 709/4885CYP4A11 368/4885LMNA 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.