Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 12/20 | 0.46 |
| ▸ | APOB | P04114 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.41 |
| ▸ | MICA | Q29983 | 2/20 | 0.41 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6669985 | 0.90 | PARP10 (0.40) | MTTPAPOBNTRK1 | |
| SCHEMBL6670740 | 0.79 | NTRK1 (0.47) | MTTPAPOBNTRK1KLRK1MICA | |
| SCHEMBL6800720 | 0.79 | KDM4E (0.47) | MTTPAPOBKDM4EKLRK1MICA | |
| SCHEMBL6645543 | 0.76 | MTTP (0.61) | MTTPAPOBKDM4ESMOGAA | |
| SCHEMBL14288688 | 0.76 | MTTP (0.52) | MTTPAPOBKDM4EKLRK1MICA | |
| Hydrochloric Acid SCHEMBL6803931 | 0.75 | MTTP (0.60) | MTTPAPOBKDM4ESMOGAA | |
| SCHEMBL533119 | 0.75 | MTTP (0.48) | MTTPAPOBKDM4EKLRK1MICA | |
| SCHEMBL6801395 | 0.73 | SMO (0.47) | MTTPAPOBKDM4ESMOGAA | |
| SCHEMBL6803527 | 0.73 | SMO (0.47) | MTTPAPOBKDM4ESMO | |
| SCHEMBL6222007 | 0.70 | MTTP (0.61) | MTTPAPOBKDM4ENTRK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | MTTP 108/4885APOB 1/4885KDM4E 2600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.