Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 3/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | MTTP | P55157 | 2/20 | 0.38 |
| ▸ | APOB | P04114 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809331 | 0.90 | MTTP (0.46) | NTRK1MTTPAPOB | |
| SCHEMBL6670637 | 0.81 | ALDH1A1 (0.48) | NTRK1FABP4RXFP1ALDH1A1 | |
| SCHEMBL6663843 | 0.80 | NOTUM (0.44) | MTTPAPOBFABP4HCRTR1HCRTR2 | |
| SCHEMBL6665641 | 0.77 | APOB (0.51) | PARP10PARP11MTTPAPOBRXFP1 | |
| Hydrochloric Acid SCHEMBL6662670 | 0.76 | APOB (0.50) | PARP10PARP11MTTPAPOBRXFP1 | |
| SCHEMBL5111860 | 0.76 | MTTP (0.40) | NTRK1MTTPAPOBFABP4FABP5 | |
| SCHEMBL6665293 | 0.74 | SORT1 (0.40) | NTRK1MTTPAPOBSORT1 | |
| SCHEMBL6667054 | 0.74 | SORT1 (0.40) | NTRK1SORT1 | |
| SCHEMBL6800720 | 0.70 | KDM4E (0.47) | MTTPAPOBALDH1A1 | |
| SCHEMBL7084242 | 0.70 | MAPT (0.58) | NTRK1MTTPFABP4RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |