Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 12/20 | 0.48 |
| ▸ | APOB | P04114 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.42 |
| ▸ | MICA | Q29983 | 2/20 | 0.42 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5111860 | 0.90 | MTTP (0.40) | MTTPAPOBKDM4EALDH1A1KMT2A | |
| SCHEMBL14288688 | 0.89 | MTTP (0.52) | MTTPAPOBKDM4EALDH1A1GAA | |
| SCHEMBL8318404 | 0.89 | L3MBTL1 (0.42) | ALDH1A1GAALMNAMAPTSMN1; SMN2 | |
| SCHEMBL532902 | 0.78 | L3MBTL1 (0.43) | MTTPKDM4EALDH1A1GAALMNA | |
| SCHEMBL8320252 | 0.78 | ALDH1A1 (0.46) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL532826 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL532809 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL533307 | 0.76 | F10 (0.43) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL6809331 | 0.75 | MTTP (0.46) | MTTPAPOBKDM4EGAAKLRK1 | |
| SCHEMBL533138 | 0.75 | NPC1 (0.46) | KDM4EALDH1A1LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415760-A2 | CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2012-02-08 | — | — | EP | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |
| US-7319111-B2 | Phenylenediamine Urotensin-II receptor antagonists and CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-01-15 | — | — | US | disclosed |