Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.67 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.49 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809332 | 1.00 | PTGS2 (0.67) | PTGS2FAAHGAAHTR2AKMT2A | |
| SCHEMBL9551669 | 0.85 | PTGS2 (0.55) | PTGS2FAAHGAAHTR2APTGS1 | |
| SCHEMBL6809302 | 0.82 | ALDH1A1 (0.55) | GAAHTR2AKMT2AALOX5BCL9 | |
| SCHEMBL6810222 | 0.82 | ALDH1A1 (0.55) | GAAHTR2AKMT2AALOX5BCL9 | |
| SCHEMBL11678768 | 0.82 | PTGS2 (0.75) | PTGS2FAAHGAAHTR2APTGS1 | |
| SCHEMBL14201191 | 0.81 | PTGS2 (0.72) | PTGS2FAAHHTR2APTGS1LMNA | |
| SCHEMBL29179760 | 0.79 | PTGS2 (0.70) | PTGS2FAAHHTR2APTGS1LMNA | |
| SCHEMBL2884860 | 0.79 | PTGS2 (0.70) | PTGS2FAAHHTR2APTGS1LMNA | |
| SCHEMBL5715396 | 0.78 | LOXL2 (0.55) | PTGS2FAAHKMT2ATRPV1LMNA | |
| SCHEMBL11228059 | 0.78 | PTGS2 (0.76) | PTGS2FAAHHTR2APTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040014161-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2004-01-22 | — | — | US | disclosed |
| EP-1090139-A1 | PH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | Thermogen, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067420-A1 | pH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | THERMOGEN, INC. (US) | 1999-12-29 | — | — | WO | disclosed |