Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810222 | 1.00 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MGLLKMT2AMEN1 | |
| SCHEMBL20943611 | 0.84 | MGLL (0.54) | ALDH1A1SMN1; SMN2MGLLKMT2AMEN1 | |
| SCHEMBL6809332 | 0.82 | PTGS2 (0.67) | KMT2AGAAHTR2ABCL9CTNNB1 | |
| SCHEMBL6809334 | 0.82 | PTGS2 (0.67) | KMT2AGAAHTR2ABCL9CTNNB1 | |
| SCHEMBL27165284 | 0.82 | MGLL (0.53) | ALDH1A1SMN1; SMN2MGLLKMT2AGAA | |
| SCHEMBL1046956 | 0.82 | L3MBTL1 (0.61) | ALDH1A1MGLLKMT2AMEN1GAA | |
| SCHEMBL10029026 | 0.82 | L3MBTL1 (0.61) | ALDH1A1MGLLKMT2AMEN1GAA | |
| SCHEMBL4683792 | 0.81 | GAA (0.60) | ALDH1A1SMN1; SMN2MGLLKMT2AMEN1 | |
| Iodide SCHEMBL28946796 | 0.81 | L3MBTL1 (0.59) | ALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8818613 | 0.80 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MGLLKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4709082-A | 2-phenylpropionic acid esters, method for optical resolution thereof and optically active substance thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1987-11-24 | — | — | US | claimed |
| US-20040014161-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2004-01-22 | — | — | US | disclosed |
| US-20020177180-A1 | pH-indicator based assay for selective enzymes | THERMOGEN, INC. | 2002-11-28 | — | — | US | disclosed |
| EP-1090139-A1 | PH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | Thermogen, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067420-A1 | pH-INDICATOR BASED ASSAY FOR SELECTIVE ENZYMES | THERMOGEN, INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| EP-0179487-B1 | 2-PHENYLPROPIONIC ACID ESTERS, METHOD FOR OPTICAL RESOLUTION THEREOF AND OPTICALLY ACTIVE SUBSTANCE THEREOF | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-08-10 | — | — | EP | disclosed |
| US-4709082-A | 2-phenylpropionic acid esters, method for optical resolution thereof and optically active substance thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0179487-A1 | 2-Phenylpropionic acid esters, method for optical resolution thereof and optically active substance thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-04-30 | — | — | EP | disclosed |