Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.62 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813826 | 0.88 | ALDH1A1 (0.56) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL1648045 | 0.87 | ALDH1A1 (0.73) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL6814409 | 0.85 | KDM4E (0.54) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL9057831 | 0.83 | POLB (1.00) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL9057835 | 0.83 | POLB (1.00) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL6546267 | 0.82 | POLB (0.57) | KDM4EALDH1A1POLBL3MBTL1RAB9A | |
| SCHEMBL8847023 | 0.81 | ALDH1A1 (0.64) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL344398 | 0.80 | FOLH1 (0.70) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL8846998 | 0.80 | ALDH1A1 (0.64) | KDM4EALDH1A1POLBL3MBTL1FOLH1 | |
| SCHEMBL10089235 | 0.80 | FOLH1 (0.69) | KDM4EALDH1A1POLBL3MBTL1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1242983-C | Phenoxyacetic acid derivatives and medicinal compositions containing the same | KISSEI PHARMACEUTICAL (JP) | 2006-02-22 | — | — | CN | disclosed |
| EP-1095932-B1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6538152-B1 | Obesity, hyperglycemia, urinary incontinence, intestinal or biliary calculi hypermotility, pollakiuria and depression treatment | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2003-03-25 | — | — | US | disclosed |
| CN-1308603-A | Phenoxyacetic acid derivatives and medicinal compositions containing the same | KISSEI PHARMACEUTICAL (JP) | 2001-08-15 | — | — | CN | disclosed |
| EP-1095932-A1 | PHENOXYACETIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-05-02 | — | — | EP | disclosed |