Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.62 |
| ▸ | F10 | P00742 | 6/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6950435 | 0.90 | ITGB3 (0.75) | ITGB3ITGA2BMAPTPLAU | |
| SCHEMBL6343991 | 0.87 | ITGB3 (0.81) | ITGB3ITGA2BF10F2 | |
| SCHEMBL6955908 | 0.85 | ITGB3 (0.66) | ITGB3ITGA2BMEN1GLAMAPT | |
| SCHEMBL6803277 | 0.84 | ITGB3 (0.60) | ITGB3ITGA2BF10F2PLAU | |
| Hydrochloric Acid SCHEMBL6958546 | 0.83 | ITGB3 (0.72) | ITGB3ITGA2BMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL6950979 | 0.83 | ITGB3 (0.59) | ITGB3ITGA2BF10F2PLAU | |
| Hydrochloric Acid SCHEMBL6953858 | 0.83 | ITGB3 (0.59) | ITGB3ITGA2BF10F2PLAU | |
| SCHEMBL6810058 | 0.82 | ITGB3 (0.58) | ITGB3ITGA2BMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL6955140 | 0.82 | ITGB3 (0.62) | ITGB3ITGA2BMEN1GLAMAPT | |
| SCHEMBL6346160 | 0.82 | ITGB3 (0.50) | ITGB3ITGA2BMEN1GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044225-A1 | Chiral and achiral synthesis of 2-acyl substituted chromanes and their derivatives | MILLENNIUM PHARMACEUTICALS, INC. | 2004-03-04 | — | — | US | disclosed |
| WO-2001092249-A2 | CHIRAL AND ACHIRAL SYNTHESIS OF 2-ACYL SUBSTITUTED CHROMANES AND THEIR DERIVATIVES | COR THERAPEUTICS, INC. (US) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044225-A1 | Chiral and achiral synthesis of 2-acyl substituted chromanes and their derivatives | ACAT2, ACACA, COASY | ITGB3 203/4885ITGA2B 395/4885F10 138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.