Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.46 |
| ▸ | ITGAV | P06756 | 8/20 | 0.46 |
| ▸ | BTK | Q06187 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6810232 | 1.00 | ITGB3 (0.46) | ITGB3ITGAVBTKADORA1CCNA2 | |
| SCHEMBL6805719 | 0.95 | BTK (0.42) | ITGB3ITGAVBTKADORA1CCNA2 | |
| SCHEMBL4644200 | 0.95 | BTK (0.42) | ITGB3ITGAVBTKADORA1CCNA2 | |
| SCHEMBL4640963 | 0.88 | ITGB3 (0.46) | ITGB3ITGAVADORA1TSHR | |
| SCHEMBL4640954 | 0.88 | ITGB3 (0.46) | ITGB3ITGAVADORA1TSHR | |
| SCHEMBL4640279 | 0.88 | ITGB3 (0.48) | ITGB3ITGAVBTKADORA1 | |
| SCHEMBL4640271 | 0.88 | ITGB3 (0.48) | ITGB3ITGAVBTKADORA1 | |
| SCHEMBL6810244 | 0.84 | BTK (0.42) | BTKADORA1CCNA2CDK2CDK5 | |
| SCHEMBL6805722 | 0.83 | BTK (0.41) | BTKADORA1CCNA2CDK2CDK5 | |
| SCHEMBL6804197 | 0.81 | ITGB3 (0.47) | ITGB3ITGAVADORA1CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |