Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 4/20 | 0.64 |
| ▸ | DHFR | P00374 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CTSG | P08311 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253328 | 0.91 | ALDH1A1 (0.68) | PIK3CGDHFRALDH1A1KDM4EMTOR | |
| SCHEMBL6819013 | 0.83 | NOS1 (0.56) | PIK3CGDHFRALDH1A1KDM4ELMNA | |
| SCHEMBL14524242 | 0.82 | PIK3CG (0.69) | PIK3CGDHFRALDH1A1KDM4EMTOR | |
| SCHEMBL6811620 | 0.79 | NUDT1 (0.45) | PIK3CGDHFRALDH1A1KDM4EMTOR | |
| SCHEMBL3746280 | 0.78 | PIK3CG (1.00) | PIK3CGDHFRALDH1A1KDM4EMTOR | |
| SCHEMBL6816554 | 0.77 | NOS1 (0.50) | PIK3CGDHFRALDH1A1KDM4ETP53 | |
| SCHEMBL3733715 | 0.77 | PTPN1 (0.55) | PIK3CGDHFRADORA2APTPN1NLRP3 | |
| SCHEMBL17407823 | 0.76 | ADORA2A (0.47) | ALDH1A1KDM4EPKMMAPTMEN1 | |
| SCHEMBL12954844 | 0.76 | PIK3CG (0.70) | PIK3CGDHFRALDH1A1KDM4EMTOR | |
| SCHEMBL6813879 | 0.75 | PIK3CG (0.64) | PIK3CGDHFRALDH1A1KDM4EMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144412-B1 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA BIOSCIENCE NV (BE) | 2004-09-29 | — | — | EP | claimed |