Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8886846 | 0.73 | ABAT (0.39) | KMT2AMAPTGPR139CTSLITGB3 | |
| SCHEMBL14417102 | 0.73 | GPR139 (0.52) | KMT2AMAPTALDH1A1GPR139MEN1 | |
| SCHEMBL1055212 | 0.73 | GPR139 (0.52) | KMT2AMAPTALDH1A1GPR139MEN1 | |
| SCHEMBL8886828 | 0.71 | MMP2 (0.36) | KMT2AMAPTGPR139SMN1; SMN2GAA | |
| SCHEMBL8886821 | 0.71 | CTSS (0.41) | KMT2AMAPTALDH1A1GPR139CTSL | |
| SCHEMBL8132701 | 0.70 | MME (0.44) | KMT2AMAPTALDH1A1GPR139ITGB3 | |
| SCHEMBL7515133 | 0.70 | KDM4E (0.59) | KMT2AMAPTGPR139CTSLMEN1 | |
| SCHEMBL7293621 | 0.70 | KDM4E (0.59) | KMT2AMAPTGPR139CTSLMEN1 | |
| SCHEMBL8595095 | 0.69 | GPR139 (0.55) | KMT2AMAPTALDH1A1GPR139ITGB3 | |
| SCHEMBL9067652 | 0.68 | GPR139 (0.57) | KMT2AMAPTALDH1A1GPR139MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799050-B1 | RADIOLABELED ANNEXIN-GALACTOSE CLUSTER CONJUGATES | NEORX CORP (US) | 2004-08-11 | — | — | EP | claimed |