Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.54 |
| ▸ | HTR1D | P28221 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808322 | 0.84 | HTR1D (0.76) | SLC6A4HTR1DDRD2ADRA1DHTR1B | |
| SCHEMBL6808289 | 0.79 | HTR1A (0.59) | SLC6A4DRD2HTR1AKDM4EGMNN | |
| SCHEMBL6811593 | 0.78 | HTR1D (0.53) | SLC6A4HTR1DDRD2ADRA1DHTR1B | |
| SCHEMBL6976036 | 0.75 | HTR1A (0.63) | SLC6A4HTR1DDRD2ADRA1DHTR1B | |
| SCHEMBL7214517 | 0.75 | DRD2 (0.60) | SLC6A4HTR1DDRD2HTR1AHTR2A | |
| SCHEMBL6811109 | 0.73 | HTR1D (0.78) | SLC6A4HTR1DDRD2ADRA1DHTR1B | |
| SCHEMBL6811583 | 0.72 | SIGMAR1 (0.31) | HTR1DHTR1A | |
| SCHEMBL7213620 | 0.71 | HTR1D (0.56) | SLC6A4HTR1DDRD2HTR1AKDM4E | |
| SCHEMBL6808570 | 0.71 | HTR1D (0.65) | SLC6A4HTR1DDRD2ADRA1DHTR1B | |
| SCHEMBL7220147 | 0.70 | HTR1D (0.51) | SLC6A4HTR1DDRD2ADRA1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY | 2004-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122001-A1 | Pharmaceutical compounds | CYP2D6, LPXN, CYP1B1 | SLC6A4 1958/4885HTR1D 124/4885DRD2 1606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.