Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 10/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 10/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.47 |
| ▸ | PLD2 | O14939 | 1/20 | 0.46 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807443 | 0.94 | ITGB1 (0.50) | ITGB1ITGA4CTSBCTSSCTSK | |
| SCHEMBL6807923 | 0.91 | CTSB (0.48) | ITGB1ITGA4CTSBCTSSCTSK | |
| SCHEMBL6807468 | 0.91 | ITGB1 (0.54) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6812370 | 0.85 | PLD1 (0.47) | ITGB1ITGA4CTSBCTSSCTSK | |
| SCHEMBL6807415 | 0.84 | ITGA4 (0.50) | ITGB1ITGA4ITGA2ITGB7OPRK1 | |
| SCHEMBL5779538 | 0.82 | OPRK1 (0.51) | CTSBCTSSCTSKOPRK1PLD2 | |
| SCHEMBL6808097 | 0.78 | ITGB1 (0.54) | ITGB1ITGA4ITGA2ITGB7L3MBTL1 | |
| SCHEMBL5781119 | 0.77 | PLD1 (0.50) | CTSBCTSSCTSKOPRK1PLD2 | |
| SCHEMBL5780094 | 0.77 | CTSB (0.58) | CTSBCTSSCTSKOPRK1PLD2 | |
| SCHEMBL6802711 | 0.75 | CALCRL (0.63) | ITGB1ITGA4OPRM1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039040-A1 | Urea derivative and adhesive-molecule inhibitor containing the same as active ingredient | TORAY INDUSTRIES, INC. (JP) | 2004-02-26 | — | — | US | disclosed |
| EP-1323709-A1 | UREA DERIVATIVE AND ADHESIVE-MOLECULE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2003-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039040-A1 | Urea derivative and adhesive-molecule inhibitor containing the same as active ingredient | ICAM1, VCAM1, EPCAM | ITGB1 55/4885ITGA4 221/4885CTSB 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.