SCHEMBL6817469

SCHEMBL6817469

CCOC(=O)c1ccccc1OC(=O)c1ccc(CC)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.60
RAB9A P51151 2/20 0.60
TSHR P16473 1/20 0.59
SLC6A3 Q01959 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.52
MAPT P10636 3/20 0.52
ALDH1A1 P00352 3/20 0.51
HSD17B10 Q99714 1/20 0.51
LMNA P02545 2/20 0.49
KDM4E B2RXH2 1/20 0.49
PRSS1 P07477 1/20 0.49
ACR P10323 1/20 0.49
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
GAA P10253 1/20 0.48
HSPA1A P0DMV8 1/20 0.47
PTPN7 P35236 1/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7210223 0.95 TSHR (0.65) NPC1RAB9ATSHRSLC6A3SMN1; SMN2
SCHEMBL6813788 0.94 TSHR (0.62) NPC1RAB9ATSHRSLC6A3SMN1; SMN2
SCHEMBL6812697 0.91 TSHR (0.59) NPC1RAB9ATSHRSLC6A3SMN1; SMN2
SCHEMBL5706020 0.91 SLC6A3 (0.69) NPC1RAB9ATSHRSLC6A3SMN1; SMN2
SCHEMBL6439342 0.90 SLC6A3 (0.72) NPC1RAB9ATSHRSLC6A3SMN1; SMN2
SCHEMBL6564035 0.90 CA12 (0.63) NPC1RAB9ATSHRSLC6A3SMN1; SMN2
SCHEMBL8499592 0.90 SLC6A3 (0.68) NPC1RAB9ATSHRSLC6A3SMN1; SMN2
SCHEMBL7641505 0.90 SLC6A3 (0.59) NPC1RAB9ATSHRSLC6A3SMN1; SMN2
SCHEMBL6813025 0.88 TSHR (0.51) NPC1RAB9ATSHRSLC6A3SMN1; SMN2
SCHEMBL5706055 0.87 SLC6A3 (0.56) NPC1RAB9ATSHRSLC6A3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed