SCHEMBL6564035

SCHEMBL6564035

CCOC(=O)c1ccccc1OC(=O)c1ccc(O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.63
CA1 P00915 3/20 0.63
CA2 P00918 3/20 0.63
CA7 P43166 3/20 0.63
CA9 Q16790 3/20 0.63
CA14 Q9ULX7 3/20 0.63
ESR1 P03372 2/20 0.63
ESR2 Q92731 1/20 0.63
TSHR P16473 2/20 0.57
SLC6A3 Q01959 1/20 0.55
LMNA P02545 2/20 0.51
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
ELANE P08246 1/20 0.48
PRTN3 P24158 1/20 0.48
PRSS1 P07477 1/20 0.48
ACR P10323 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7210223 0.94 TSHR (0.65) CA12CA1CA2CA7CA9
SCHEMBL6813788 0.92 TSHR (0.62) CA12CA1CA2CA7CA9
SCHEMBL6812697 0.90 TSHR (0.59) ESR1ESR2TSHRSLC6A3LMNA
SCHEMBL6817469 0.90 NPC1 (0.60) CA12CA1CA2CA7CA9
SCHEMBL5706020 0.89 SLC6A3 (0.69) TSHRSLC6A3LMNAKDM4EALDH1A1
SCHEMBL7621532 0.89 ALDH1A1 (0.65) CA12CA1CA2CA7CA9
SCHEMBL8499592 0.88 SLC6A3 (0.68) TSHRSLC6A3LMNAKDM4EALDH1A1
SCHEMBL7641505 0.88 SLC6A3 (0.59) TSHRSLC6A3LMNAKDM4EALDH1A1
SCHEMBL6439342 0.88 SLC6A3 (0.72) TSHRSLC6A3LMNAKDM4EALDH1A1
SCHEMBL6565194 0.86 TSHR (0.67) ESR1TSHRSLC6A3LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140004071-A1 Thermochromic Dental Material BROWN WILLIAM STEVEN (US) 2014-01-02 US disclosed
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
EP-0863022-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2002-09-18 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0748698-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 2001-08-22 EP disclosed
US-6184300-B1 USEFUL AS HEAT-INSULATING MATERIAL, ORGANIC PIGMENT, OR OPACIFYING AGENT, AND AS HEAT-INSULATING INTERLAYER TO BE FORMED IN THERMAL RECORDING MATERIAL NIPPON ZEON CO., LTD. (JP) 2001-02-06 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed
US-6028030-A CONTAINING AN IMAGE PRESERVATIVE/STABILIZER POLYUREA IN THE THERMAL COLOR DEVELOPING LAYER CONTAINING DYE PRECURSOR NIPPON PAPER INDUSTRIE CO., LTD. (JP) 2000-02-22 US disclosed
EP-0699662-B1 Novel urea (thiourea) derivative and thermal recording sheet using same JUJO PAPER CO LTD (JP) 1998-10-21 EP disclosed
EP-0863022-A1 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1998-09-09 EP disclosed
EP-0559386-A2 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-09-08 EP disclosed
EP-0391434-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-06-30 EP disclosed
EP-0289041-B1 THERMOSENSITIVE RECORDING SHEET JUJO PAPER CO., LTD. (JP) 1993-03-24 EP disclosed
US-5096873-A Containign a support, color developer layer with a basic leuco dye in it; high density speed recording, image storage stability JUJO PAPER CO., LTD. (JP) 1992-03-17 US disclosed
US-4971942-A Colorless basic chromogenic cye, divinyl compound, fluorane-type leuco dye JUJO PAPER CO., LTD. (JP) 1990-11-20 US disclosed
EP-0391434-A1 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1990-10-10 EP disclosed
US-4918044-A LEUCO DYE, COLOR DEVELOPER, BIPHENYL TOLYL ETHER SENSITIZER, STABLE, HIGH DENSITY, HIGH SPEED RECORDING JUJO PAPER CO., LTD. (JP) 1990-04-17 US disclosed
US-4853362-A Heat-sensitive recording sheet JUJO PAPER CO., LTD. (JP) 1989-08-01 US disclosed
EP-0289041-A2 Thermosensitive recording sheet JUJO PAPER CO., LTD. (JP) 1988-11-02 EP disclosed
US-4573062-A HYDROXYBENZ/YLOXYBENZOIC ACID COLOR DEVELOPER AND LEUCO DYE JUJO PAPER CO., LTD. (JP) 1986-02-25 US disclosed