SCHEMBL8499592

SCHEMBL8499592

CCOC(=O)c1ccccc1OC(=O)c1ccc(C(=O)OC)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.68
MAPT P10636 3/20 0.58
PRSS1 P07477 1/20 0.58
ACR P10323 1/20 0.58
TSHR P16473 2/20 0.57
KMT2A Q03164 3/20 0.53
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
SMN1; SMN2 Q16637 4/20 0.51
KDM4E B2RXH2 3/20 0.51
LMNA P02545 2/20 0.51
ALDH1A1 P00352 4/20 0.50
HTT P42858 3/20 0.50
GAA P10253 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 1/20 0.50
HPGD P15428 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6439342 0.97 SLC6A3 (0.72) SLC6A3MAPTPRSS1ACRTSHR
SCHEMBL5706074 0.94 SLC6A3 (0.72) SLC6A3MAPTPRSS1ACRTSHR
SCHEMBL7210223 0.94 TSHR (0.65) SLC6A3MAPTPRSS1ACRTSHR
SCHEMBL6813788 0.92 TSHR (0.62) SLC6A3MAPTPRSS1ACRTSHR
SCHEMBL6817469 0.90 NPC1 (0.60) SLC6A3MAPTPRSS1ACRTSHR
SCHEMBL6812697 0.90 TSHR (0.59) SLC6A3MAPTPRSS1ACRTSHR
SCHEMBL5706020 0.89 SLC6A3 (0.69) SLC6A3MAPTTSHRKMT2ANPC1
SCHEMBL5706055 0.89 SLC6A3 (0.56) SLC6A3MAPTPRSS1ACRTSHR
SCHEMBL7641505 0.88 SLC6A3 (0.59) SLC6A3MAPTPRSS1ACRTSHR
SCHEMBL6564035 0.88 CA12 (0.63) SLC6A3MAPTPRSS1ACRTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed