Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | APAF1 | O14727 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.57 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | FABP3 | P05413 | 2/20 | 0.56 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.56 |
| ▸ | CDC25B | P30305 | 4/20 | 0.55 |
| ▸ | CCR2 | P41597 | 5/20 | 0.55 |
| ▸ | CCR1 | P32246 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30462469 | 0.88 | FABP4 (0.57) | FABP4KDM4EAPAF1RECQLCASP6 | |
| SCHEMBL28550164 | 0.88 | FABP4 (0.57) | FABP4KDM4EAPAF1RECQLCASP6 | |
| SCHEMBL6141415 | 0.83 | TAS2R14 (0.67) | FABP4CCR2CCR1AKR1C3AKR1C2 | |
| SCHEMBL446113 | 0.83 | HTT (0.77) | KDM4ERECQLHTTCCR2CCR1 | |
| SCHEMBL29682980 | 0.83 | HTT (0.77) | KDM4ERECQLHTTCCR2CCR1 | |
| SCHEMBL30320327 | 0.83 | FABP4 (0.80) | FABP4KDM4EAPAF1RECQLCASP6 | |
| SCHEMBL355549 | 0.83 | FABP4 (0.80) | FABP4KDM4EAPAF1RECQLCASP6 | |
| SCHEMBL30638203 | 0.83 | KDM4E (0.75) | FABP4KDM4EAPAF1RECQLCASP6 | |
| SCHEMBL4246571 | 0.83 | KDM4E (0.75) | FABP4KDM4EAPAF1RECQLCASP6 | |
| SCHEMBL9953689 | 0.81 | KDM4E (0.83) | FABP4KDM4EAPAF1RECQLCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142993-A1 | Inhibitors of HCV NS5B polymerase | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | claimed |
| US-20040142993-A1 | Inhibitors of HCV NS5B polymerase | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142993-A1 | Inhibitors of HCV NS5B polymerase | POLRMT, POLR1E, CTDSP1 | FABP4 4112/4885KDM4E 2739/4885APAF1 1922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.