SCHEMBL6813640

SCHEMBL6813640

COC(=O)c1ccccc1OC(=O)Oc1ccc(C2CCCCC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TSHR P16473 1/20 0.48
SLC6A3 Q01959 1/20 0.47
MAPT P10636 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 5/20 0.43
HPGD P15428 3/20 0.43
HSD17B10 Q99714 2/20 0.43
KMT2A Q03164 3/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP1A2 P05177 1/20 0.41
CASP1 P29466 1/20 0.41
ATM Q13315 1/20 0.40
DDB1 Q16531 1/20 0.40
CRBN Q96SW2 1/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5706061 0.87 TSHR (0.44) ALDH1A1TSHRMAPTSMN1; SMN2HSD17B10
SCHEMBL6575472 0.84 ALDH1A1 (0.51) ALDH1A1TSHRSLC6A3MAPTKDM4E
SCHEMBL6575475 0.82 ALDH1A1 (0.57) ALDH1A1TSHRMAPTSMN1; SMN2KDM4E
SCHEMBL5706035 0.80 SLC6A3 (0.58) ALDH1A1TSHRSLC6A3MAPTSMN1; SMN2
SCHEMBL248211 0.80 ALDH1A1 (0.51) ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A
SCHEMBL14774960 0.80 SMN1; SMN2 (0.50) ALDH1A1MAPTSMN1; SMN2KMT2AMEN1
SCHEMBL1282392 0.80 SLC6A3 (0.66) ALDH1A1TSHRSLC6A3MAPTKDM4E
SCHEMBL238310 0.80 HDAC8 (0.49) ALDH1A1MAPTSMN1; SMN2KDM4EKMT2A
SCHEMBL9769792 0.80 CASP1 (0.48) ALDH1A1TSHRSLC6A3MAPTSMN1; SMN2
SCHEMBL4384563 0.79 SLC6A3 (0.56) ALDH1A1TSHRSLC6A3MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976772-B1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LTD (JP) 2004-06-16 EP disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
US-6303734-B1 HIGH STABILITY TO THE DETERIORATION OF THE COLOR OF CHIPS STORED IN AIR AT ROOM TEMPERATURE BY SUPPRESSING THE RELATIVE INTENSITY OF FLUORESCENT LIGHT TO 4.0 X.10(TO-3) OR BELOW TEIJIN LIMITED (JP) 2001-10-16 US disclosed
EP-0985696-A1 STABILIZED AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-15 EP disclosed
EP-0976772-A1 PROCESS FOR PRODUCING POLYCARBONATE RESIN TEIJIN LIMITED (JP) 2000-02-02 EP disclosed
EP-0764673-B1 Process for the production of polycarbonate TEIJIN LTD (JP) 1999-11-17 EP disclosed
US-5696222-A MELT POLYCONDENSATION OF AN AROMATIC DIHYDROXY COMPOUND AND DIPHENYLCARBONATE, THEN ADDING A SPECIFIC CARBONATE OR CARBOCYCLIC ESTER TO FORM TERMINAL BLOCKED POLYCARBONATE TEIJIN LIMITED (JP) 1997-12-09 US disclosed
EP-0764673-A2 Process for the production of polycarbonate TEIJIN LIMITED (JP) 1997-03-26 EP disclosed