Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | CRHR1 | P34998 | 9/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817533 | 0.83 | HSP90AA1 (0.37) | ACP1CRHR1CRHR2CYP1A2CYP3A4 | |
| SCHEMBL6817674 | 0.82 | CRHR1 (0.36) | CRHR1CRHR2 | |
| SCHEMBL6818015 | 0.80 | ACP1 (0.36) | ACP1CRHR1CRHR2NPC1RAB9A | |
| SCHEMBL6818255 | 0.79 | CRHR1 (0.36) | CRHR1CRHR2 | |
| SCHEMBL6817843 | 0.78 | SCN9A (0.37) | ACP1CRHR1SCN9A | |
| SCHEMBL6814612 | 0.78 | BCHE (0.30) | — | |
| SCHEMBL6817664 | 0.77 | KMT5A (0.34) | ACP1CRHR1 | |
| SCHEMBL6082284 | 0.76 | NR1I2 (0.38) | — | |
| SCHEMBL6817679 | 0.75 | STK17B (0.35) | SMN1; SMN2 | |
| SCHEMBL6818651 | 0.71 | BRD4 (0.34) | CYP3A4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004031189-A1 | PYRIDINO AND PYRIMIDINO PYRAZINONES FOR TREATMENT OF ANXIETY AND DEPRESSION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2004-04-15 | — | — | WO | disclosed |