Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29590253 | 0.86 | IDO1 (0.59) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL11142136 | 0.86 | IDO1 (0.59) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL12989536 | 0.85 | IDO1 (0.49) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL29855606 | 0.85 | IDO1 (0.49) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL31564976 | 0.79 | IDO1 (0.51) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL8308445 | 0.78 | IDO1 (0.58) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL817976 | 0.76 | IDO1 (0.56) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL2175357 | 0.76 | IDO1 (0.61) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL30908530 | 0.76 | IDO1 (0.56) | IDO1HTR2COPRM1DRD3AVPR1A | |
| SCHEMBL28735117 | 0.76 | IDO1 (0.62) | IDO1CTSVCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266673-A1 | Long lasting natriuretic peptide derivatives | CONJUCHEM INC (CA) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266673-A1 | Long lasting natriuretic peptide derivatives | NPPA, NPR1, NPR3 | IDO1 3670/4885HTR2C 3515/4885OPRM1 1912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.