Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12519883 | 0.74 | LMNA (0.37) | KMT2AMEN1THRBGAAALDH1A1 | |
| SCHEMBL18742846 | 0.73 | — | — | |
| SCHEMBL13647772 | 0.73 | ACHE (0.37) | KMT2AMEN1THRBGAAALDH1A1 | |
| SCHEMBL7529638 | 0.72 | ALDH1A1 (0.33) | KMT2AMEN1THRBGAAALDH1A1 | |
| SCHEMBL7529634 | 0.72 | MEN1 (0.34) | KMT2AMEN1THRBGAAALDH1A1 | |
| SCHEMBL12445270 | 0.72 | ALDH1A1 (0.32) | KMT2AMEN1THRBGAAALDH1A1 | |
| SCHEMBL15478105 | 0.71 | ALDH1A1 (0.38) | KMT2AGAAALDH1A1MAPTKDM4E | |
| SCHEMBL2113918 | 0.71 | HCAR2 (0.45) | CYP1A2 | |
| SCHEMBL986535 | 0.70 | ALDH1A1 (0.40) | KMT2AGAAALDH1A1MAPTKDM4E | |
| SCHEMBL4698495 | 0.68 | MEN1 (0.42) | KMT2AMEN1GAANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441249-B2 | ACID CATALYSIS OF ISOPHERONE, DISTILLATION, OXIDATION IN AMORPHOUS CARBON AND BASE FORMING 4-OXOISOPHORONE WHICH REACTS WITH ACID ANHYDRIDE/CARBOXYLIC ACID TO FORM COMPOUND HYDROLYZED TO TRIMETHYLHYDROQUINONE; EFFICIENCY; VITAMIN E | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 2002-08-27 | — | — | US | claimed |
| US-8895497-B2 | Cathepsin S inhibitors | DCB-USA, LLC (US) | 2014-11-25 | — | — | US | disclosed |
| WO-2011069149-A2 | CATHEPSIN S INHIBITORS | DCB-USA LLC (US) | 2011-06-09 | — | — | WO | disclosed |
| US-20070232811-A1 | STERICALLY HINDERED PI-BRIDGE NONLINEAR OPTICAL CHROMOPHORES, PROCESSES INCLUDING SAME, AND DEVICES THEREFROM | LUMERA CORPORATION (US) | 2007-10-04 | — | — | US | disclosed |
| US-7206111-B2 | Sterically hindered PI-bridge nonlinear optical chromophores, processes including same, and devices therefrom | LUMERA CORPORATION (US) | 2007-04-17 | — | — | US | disclosed |
| EP-1760080-A1 | Design and synthesis of thiophene derived NLO materials for electro-optic applications | Lumera Corporation (US) | 2007-03-07 | — | — | EP | disclosed |
| US-6680132-B2 | Red organic electroluminescent devices | EASTMAN KODAK COMPANY | 2004-01-20 | — | — | US | disclosed |
| US-20030203234-A1 | Red organic electroluminescent devices | EASTMAN KODAK COMPANY | 2003-10-30 | — | — | US | disclosed |
| EP-1351322-A1 | Red organic electroluminescent devices | EASTMAN KODAK COMPANY (US) | 2003-10-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232811-A1 | STERICALLY HINDERED PI-BRIDGE NONLINEAR OPTICAL CHROMOPHORES, PROCESSES INCLUDING SAME, AND DEVICES THEREFROM | FARS2, ETFA, ETFB | KMT2A 4334/4885MEN1 4594/4885THRB 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.