Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834009 | 0.83 | CTSA (0.47) | KDM4EMAPTSAE1UBA2SCN10A | |
| SCHEMBL6830649 | 0.81 | KCNH2 (0.54) | KDM4EMAPTSAE1UBA2NR1H4 | |
| SCHEMBL6833875 | 0.77 | KDM4E (0.52) | KDM4EMAPTSAE1UBA2SCN10A | |
| SCHEMBL6833755 | 0.73 | KCNH2 (0.55) | KDM4EMAPTSAE1UBA2SCN10A | |
| SCHEMBL6835793 | 0.72 | KCNH2 (0.49) | NR1H4SCN10AKCNH2XDHKMT2A | |
| SCHEMBL6833154 | 0.72 | KDM4E (0.54) | KDM4EMAPTSAE1UBA2SCN10A | |
| SCHEMBL6357270 | 0.71 | SERPINE1 (0.62) | MAPTNR1H4KMT2ATDP1 | |
| SCHEMBL1317262 | 0.70 | ACLY (0.52) | CTSAHDAC1AXL | |
| SCHEMBL6834158 | 0.70 | XDH (0.54) | KDM4EMAPTSAE1UBA2SCN10A | |
| SCHEMBL1317261 | 0.69 | CTSA (0.46) | SCN10AKCNH2CTSAABL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |