Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 4/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 2/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | GAK | O14976 | 1/20 | 0.43 |
| ▸ | STK16 | O75716 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | STK3 | Q13188 | 1/20 | 0.43 |
| ▸ | STK11 | Q15831 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833875 | 0.90 | KDM4E (0.52) | KCNH2SCN10AXDHKDM1AHDAC1 | |
| SCHEMBL6357270 | 0.90 | SERPINE1 (0.62) | SERPINE1NR1H4MAPTALBPPARG | |
| SCHEMBL6833755 | 0.87 | KCNH2 (0.55) | KCNH2SCN10AXDHSERPINE1KDM1A | |
| SCHEMBL6834140 | 0.87 | SCN10A (0.54) | KCNH2SCN10AXDHSERPINE1KDM1A | |
| SCHEMBL6834158 | 0.86 | XDH (0.54) | KCNH2SCN10AXDHKDM1AHDAC1 | |
| SCHEMBL6833154 | 0.82 | KDM4E (0.54) | KCNH2SCN10AXDHSERPINE1KDM4E | |
| SCHEMBL6814812 | 0.81 | KDM4E (0.46) | KCNH2SCN10AXDHNR1H4KDM1A | |
| SCHEMBL6835793 | 0.80 | KCNH2 (0.49) | KCNH2SCN10AXDHSERPINE1NR1H4 | |
| SCHEMBL6833253 | 0.79 | GAK (0.46) | KCNH2SCN10AXDHSERPINE1ALB | |
| SCHEMBL6833179 | 0.79 | ALDH1A1 (0.66) | KDM4EMAPTALBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | KCNH2 1913/4885SCN10A 2695/4885XDH 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.