Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | GALR1 | P47211 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PARL | Q9H300 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6820982 | 0.84 | KDM4E (0.36) | LMNANLRP3L3MBTL1HCN4PDE7A | |
| SCHEMBL5964149 | 0.78 | GALR1 (0.37) | LMNANLRP3L3MBTL1HCN4RAB9A | |
| SCHEMBL5964213 | 0.64 | HSD11B1 (0.33) | LMNANLRP3L3MBTL1HCN4P2RX7 | |
| SCHEMBL5964017 | 0.62 | GRIN1 (0.36) | LMNARAB9ANPC1 | |
| SCHEMBL4959889 | 0.61 | RAB9A (0.47) | RAB9ANPC1 | |
| SCHEMBL5963561 | 0.60 | SLC6A2 (0.33) | LMNAHCN4 | |
| SCHEMBL5963628 | 0.60 | PDE7A (0.38) | LMNARAB9AGALR1PDE1APDE1B | |
| Acetone SCHEMBL7904088 | 0.56 | CYP2A6 (0.74) | L3MBTL1HSP90AA1 | |
| Acetic Acid SCHEMBL10499422 | 0.56 | CYP2A6 (0.74) | L3MBTL1HSP90AA1 | |
| SCHEMBL12528323 | 0.55 | PLA2G7 (0.44) | LMNACNR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326851-B1 | SUBSTITUTED DIPEPTIDES AS GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2004-06-30 | — | — | EP | claimed |