Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2995781 | 0.74 | IDO1 (0.52) | RAB9ANPC1TAAR1CTBP2PNMT | |
| SCHEMBL265672 | 0.74 | CTBP2 (0.55) | RAB9ANPC1CTBP2MAOAMAOB | |
| Acetic Acid SCHEMBL27865224 | 0.74 | NPC1 (0.52) | RAB9ANPC1CTBP2MAOAMAOB | |
| SCHEMBL6970211 | 0.73 | ALDH1A1 (0.45) | RAB9ANPC1ALDH1A1HTTKDM4E | |
| SCHEMBL803464 | 0.73 | IDO1 (0.50) | RAB9ANPC1TAAR1CTBP2PNMT | |
| Methyl Alcohol SCHEMBL28233464 | 0.72 | CTBP2 (0.53) | RAB9ANPC1CTBP2MAOAMAOB | |
| Acetic Acid SCHEMBL27587476 | 0.72 | NPC1 (0.50) | RAB9ANPC1CTBP2MAOAMAOB | |
| SCHEMBL1040588 | 0.71 | NOS2 (0.50) | CTBP2ALDH1A1GRIN1GRIN2BPKM | |
| SCHEMBL27796775 | 0.71 | NPC1 (0.53) | RAB9ANPC1TAAR1CTBP2MAOA | |
| SCHEMBL1293 | 0.71 | IAPP (0.55) | RAB9ANPC1TAAR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001041763-A1 | TREATMENT OF ADDICTION DISORDERS | UNIVERSITY OF CINCINNATI (US) | 2001-06-14 | — | — | WO | claimed |
| US-20080089859-A1 | ADMINISTRATION OF SLEEP RESTORATIVE AGENTS | HOLMAN ANDREW | 2008-04-17 | — | — | US | disclosed |
| US-20020165246-A1 | Administration of sleep restorative agents | HOLMAN ANDREW (US) | 2002-11-07 | — | — | US | disclosed |
| US-6300365-B1 | ADMINISTERING NON-ERGOT DOPAMINE D.SUB.2 /D.SUB.3 RECEPTOR AGONIST OR ACID ADDITION SALT COMPRISING 3(H)-INDOLONE COMPOUND FOR THERAPY OF FIBROMYALGIA | INMEDIX, LLC | 2001-10-09 | — | — | US | disclosed |
| US-6277875-B1 | FIBROMYALGIA | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2001-08-21 | — | — | US | disclosed |
| WO-2001041763-A1 | TREATMENT OF ADDICTION DISORDERS | UNIVERSITY OF CINCINNATI (US) | 2001-06-14 | — | — | WO | disclosed |
| US-4886812-A | REGULATING DOPAMINE CONCENTRATION; PARKINSON DISEASE, HYPOTENSIVE AGENT, SCHIZOPHRENIA | DR. KARL THOMAE GMBH (DE) | 1989-12-12 | — | — | US | disclosed |
| US-4843086-A | HYPOTENSIVE AGENTS, SCHIZOPHRENIA, PARKINSON'S DISEASE | BOEHRINGER INGELHEIM KG (DE) | 1989-06-27 | — | — | US | disclosed |
| US-4731374-A | PARKINSON*S DISEASE | DR. KARL THOMAE GMBH (DE) | 1988-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165246-A1 | Administration of sleep restorative agents | GAP43, PER2, PSAP | RAB9A 3709/4885NPC1 1578/4885TAAR1 2721/4885 |
| US-20080089859-A1 | ADMINISTRATION OF SLEEP RESTORATIVE AGENTS | GAP43, PER2, PSAP | RAB9A 3791/4885NPC1 1549/4885TAAR1 2924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.